Acetaminophen induced Stevens Johnson syndrome - Toxic Epidermal Necrolysis Overlap Syndrome: A rare Adverse Reaction

Stevens Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are hyper sensitive life - threatening rare dermatological reactions. In SJS TEN overlap syndrome, the extent severity of epidermal detachment is 10- 30%. Drugs like sulfonamides, nonsteroidal anti- inflammatory agents, antibiotics anticonvulsants commonest precipitants. Here, we present a case in previously normal 11 years old girl after acetaminophen intake for fever. This report intended to make paediatricians aware that adverse reaction can develop with drug which supposed be safest antipyretic paediatrics.